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№ 2024.001  —  Massachusetts Institute of Technology  —  Commencement address

Noubar Afeyan

Flagship Pioneering CEO and Moderna co-founder

Noubar Afeyan urges the MIT Class of 2024 to accept seemingly impossible missions, drawing on his childhood in war-torn Beirut, the 'Mission Impossible' theme, and Moderna's rapid development of a COVID-19 vaccine. He outlines three actions for tackling hard challenges—imagine, innovate, and immigrate—while emphasizing moral responsibility, paranoid optimism, and embracing uncertainty. He frames graduates as 'agents for good' uniquely equipped by their MIT education to confront global crises.

Key moments

  • 01 Recounting his Beirut childhood and fascination with 'Mission Impossible'
  • 02 Describing Moderna's rapid COVID-19 vaccine development
  • 03 Urging graduates to imagine, innovate, and immigrate
  • 04 Reflecting on his Armenian heritage, moral responsibility, and embracing uncertainty

Visual speech map

Noubar Afeyan at MIT, 2024

A commencement address about impossible missions, imagination, innovation, immigration, uncertainty, and public good.

Speech arc
  1. 01 Beirut childhood
  2. 02 Mission Impossible
  3. 03 Moderna
  4. 04 Imagine
  5. 05 Innovate
  6. 06 Immigrate
  7. 07 Uncertainty
  8. 08 Agents for good
01 IB

Origin

Impossible begins as a lived condition

Afeyan links childhood in war-torn Beirut, Armenian heritage, and the Mission Impossible theme to a lifelong comfort with daunting assignments.

Uncertainty

Uncertainty is not an exception; it is the operating environment.

Memory

Identity carries history, responsibility, and imagination.

Agency

The impossible becomes a prompt for action instead of paralysis.

02 MT

Case study

Moderna turns urgency into action

The COVID vaccine story becomes evidence that ambitious science needs preparation, collaboration, and motion before certainty arrives.

Platform

Capabilities built before crisis make rapid response possible.

Pressure

Innovation requires coordination, discipline, and speed under pressure.

Trust

Public good is part of the technical challenge.

03 II

Method

Imagine, innovate, immigrate

His three verbs form a method for crossing boundaries: see a different future, build toward it, and move across places, fields, and assumptions.

Imagine

Look beyond inherited constraints and rehearse a better future.

Innovate

Turn imagination into disciplined experiment and useful tools.

Immigrate

Cross borders of geography, field, identity, and assumption.

04 PP

Charge

Practice paranoid optimism

The speech closes by asking graduates to stay alert to danger while refusing cynicism, becoming agents for good in a world of hard problems.

Optimism

Optimism supplies motion; paranoia supplies rigor.

Ethics

Moral responsibility belongs inside invention.

Service

MIT graduates are asked to serve crises larger than themselves.

Ideas woven together

  • 01 Accept uncertainty
  • 02 Imagine beyond constraints
  • 03 Build before crisis
  • 04 Cross boundaries
  • 05 Use talent for public good

Core themes

imaginationinnovationimmigrationuncertaintypublic good

Transcript

The full transcript is hosted by the original publisher. Commencement Archive links to the source rather than republishing copyrighted text.

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Provenance

Verified from official archive